A preclinical study-systemic evaluation of safety on mesenchymal stem cells derived from human gingiva tissue.
Jun ZhaoJulie WangJunlong DangWangyu ZhuYaqiong ChenXimei ZhangJunliang XieBo HuFeng HuangBaoqing SunJoseph A BellantiSong Guo ZhengPublished in: Stem cell research & therapy (2019)
GMSCs are safe in various animal models of autoimmunity, even during active disease episodes, especially in monkeys. This study paves a solid road for future clinical trials of GMSCs in patients with autoimmune and inflammatory diseases.