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A preclinical study-systemic evaluation of safety on mesenchymal stem cells derived from human gingiva tissue.

Jun ZhaoJulie WangJunlong DangWangyu ZhuYaqiong ChenXimei ZhangJunliang XieBo HuFeng HuangBaoqing SunJoseph A BellantiSong Guo Zheng
Published in: Stem cell research & therapy (2019)
GMSCs are safe in various animal models of autoimmunity, even during active disease episodes, especially in monkeys. This study paves a solid road for future clinical trials of GMSCs in patients with autoimmune and inflammatory diseases.
Keyphrases
  • clinical trial
  • mesenchymal stem cells
  • endothelial cells
  • multiple sclerosis
  • oxidative stress
  • bone marrow
  • drug induced
  • phase ii
  • phase iii
  • placebo controlled