Direct oral anticoagulant plasma levels and thrombin generation on ST Genesia system.

Christian PfrepperMichael MetzeAnnelie SiegemundTristan KlöterThomas SiegemundSirak Petros

Published in: Research and practice in thrombosis and haemostasis (2020)

TG parameters measured with ST Genesia correlate with the drug levels of anti-Xa DOACs. Peak thrombin and velocity index are of special interest for the determination of residual anticoagulant effect at low drug levels. For dabigatran-treated patients, only lag time shows a correlation with the dabigatran plasma levels.

Keyphrases

atrial fibrillation
end stage renal disease
newly diagnosed
venous thromboembolism
ejection fraction
chronic kidney disease
direct oral anticoagulants
prognostic factors
peritoneal dialysis
emergency department
patient reported outcomes