Preliminary findings from the Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (DRIVE I) Study: a Randomized Controlled Trial.
Benjamin John CowlingSook-San WongJefferson J S SantosLisa TouyonJordan T OrtNaiqing YeNatalie K M KwokFaith HoSamuel M S ChengDennis K M IpMalik PeirisRichard J WebbyPatrick C WilsonSophie A ValkenburgJohn S TsangNancy H L LeungScott E HensleySarah CobeyPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2024)
In the first two years, during which influenza did not circulate, repeat vaccinees and first-time vaccinees had similar post-vaccination geometric mean titers to all four vaccine strains, indicative of similar levels of clinical protection.