The behavioral variant of Alzheimer's disease does not show a selective loss of Von Economo and phylogenetically related neurons in the anterior cingulate cortex.
Ellen H SingletonY A L PijnenburgP Gami-PatelB D C BoonF BouwmanJ M PapmaH SeelaarP ScheltensL T GrinbergS SpinaA L NanaG D RabinoviciW W SeeleyR OssenkoppeleA A DijkstraPublished in: Alzheimer's research & therapy (2022)
VENs and phylogenetically related neurons did not show a selective loss in the ACC in patients with bvAD. Our results suggest that, unlike in bvFTD, the clinical presentation in bvAD may not be related to the loss of VENs and related neurons in the ACC.