Impact of PNPLA3 and TM6SF2 polymorphisms on the prognosis of patients with MASLD and type 2 diabetes mellitus.
Natália Coelho LavradoGil Fernando SallesClaudia Regina Lopes CardosoPaulo Henrique Condeixa de FrançaMaria Fernanda Di Guimarães Gonçalves MeloNathalie Carvalho LeiteCristiane Alves Villela NogueiraPublished in: Liver international : official journal of the International Association for the Study of the Liver (2024)
In T2DM, PNPLA3 and TM6SF2 polymorphisms, individually and additively, impact MASLD severity, with an increased risk of cirrhosis and its complications.