Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?
Juliana Monte RealLudmila Rodrigues Pinto FerreiraGustavo Henrique EstevesFernanda Christtanini KoyamaMarcos Vinícius Salles DiasJoão Evangelista Bezerra-NetoEdécio Cunha-NetoFlavia Ribeiro MachadoReinaldo SalomãoLuciano César Pontes de AzevedoPublished in: Critical care (London, England) (2018)
Exosomes from patients with septic shock convey miRNAs and mRNAs related to pathogenic pathways, including inflammatory response, oxidative stress, and cell cycle regulation. Exosomes may represent a novel mechanism for intercellular communication during sepsis.