Submandibular gland involvement in oral cavity squamous cell carcinoma: a retrospective multicenter study.
Oreste IoccaChiara CopelliPaolo Garzino-DemoGuglielmo RamieriStefano RubattinoLuca SedranFabio VolpeAlfonso ManfusoFrancesco LongoGregorio Sanchez-AnicetoÁlvaro Rivero-CalleAitor García-SánchezRaul PelliniGerardo PetruzziSilvia MorettoLaith Al-QamachiHiba AgaStephen RidleyPasquale Di MaioPublished in: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery (2023)
The incidence of SMG involvement in primary OCC is rare. Therefore, exploring gland preservation as an option in selected cases would be reasonable. Future prospective studies are needed to investigate the oncological safety and the real impact on quality of life of SMG preservation.