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Occurrence of high-risk clones of Klebsiella pneumoniae ST11, ST340 and ST855 carrying the blaKPC-2, blaNDM-1, blaNDM-5 and blaNDM-7 genes from colonized and infected patients in Brazil.

Érica Maria de OliveiraElizabeth Maria Bispo BeltrãoMaria Izabely Silva PimentelAna Catarina de Souza Lopes
Published in: Journal of applied microbiology (2023)
These findings are worrying, as they have a negative impact on the scenario of antimicrobial resistance, and show the high genetic variability of K. pneumoniae and its ability to mutate resistance genes and risk of dissemination via different ST clones.
Keyphrases
  • klebsiella pneumoniae
  • antimicrobial resistance
  • multidrug resistant
  • escherichia coli
  • genome wide
  • risk assessment
  • bioinformatics analysis
  • copy number