Association of Cardiovascular Outcomes with Low-Dose Glucocorticoid Use in Patients with Rheumatoid Arthritis.

Among older, more comorbid and younger, higher cardiovascular risk patients with RA on stable DMARD therapy, glucocorticoids were associated with a dose-dependent increased risk of myocardial infarction and stroke, even at doses ≤5mg/d. By contrast, no association was noted among younger, healthier patients with RA.