A class I histone deacetylase HDA-2 is essential for embryonic development and size regulation of fertilized eggs in Caenorhabditis elegans.

Takuma UnnoHisashi TakatsukaYuto OhnishiMasahiro Ito Yukihiko Kubota

Published in: Genes & genomics (2021)

Our finding suggests that HDA-2 regulates the embryonic development in Caenorhabditis elegans by controling a specific subset of genes, and this function might be mediated by transgenerational epigenetic effect.

Keyphrases

histone deacetylase
dna methylation
genome wide
gene expression
bioinformatics analysis
genome wide identification
transcription factor