Meltdose Tacrolimus Population Pharmacokinetics and Limited Sampling Strategy Evaluation in Elderly Kidney Transplant Recipients.
Jasper KampTom C ZwartSoufian MeziyerhPaul J M van der BoogEsther E NijghKoen van DuinAiko P J de VriesDirk Jan A R MoesPublished in: Pharmaceutics (2023)
The developed population PK model adequately described the tacrolimus PK data in a population of elderly kidney transplant recipients. In addition, the developed population PK model and LSS showed an adequate estimation of tacrolimus exposure, and may therefore be used to aid in tacrolimus dose individualization.