Association of Vascular Risk Factors and CSF and Imaging Biomarkers With White Matter Hyperintensities in Former American Football Players.

Monica T Ly Fatima Tuz-Zahra Yorghos Tripodis Charles H Adler Laura J Balcer Charles B Bernick Henrik Zetterberg Kaj Blennow Elaine R Peskind Rhoda Au Sarah J Banks William B Barr Jennifer V Wethe Mark W Bondi Lisa M Delano-Wood Robert C Cantu Michael J Coleman David W Dodick Michael D McClean Jesse B Mez Joseph Palmisano Brett Martin Kaitlin Hartlage Alexander P Lin Inga K Koerte Jeffrey L Cummings Eric M Reiman Martha E Shenton Robert A Stern Sylvain Bouix Michael L Alosconull null

Published in: Neurology (2023)

and diffusion tensor imaging indices of white matter integrity showed stronger associations with WMH in the former football players. FLAIR WMH may have specific risk factors and pathologic underpinnings in RHI-exposed individuals.

Keyphrases

white matter
risk factors
high school

multiple sclerosis
high resolution

neoadjuvant chemotherapy
locally advanced

radiation therapy
photodynamic therapy