Extracellular vesicles derived from glioblastoma promote proliferation and migration of neural progenitor cells via PI3K-Akt pathway.
Jiabin PanShiyang ShengLing YeXiaonan XuYizhao MaXuanran FengLisha QiuZhaohuan FanYi WangXiaohuan XiaJialin C ZhengPublished in: Cell communication and signaling : CCS (2022)
Our findings demonstrate that EVs play a key role in intercellular communication in tumor microenvironment. Inhibition of the tumorgenic EVs-mediated PI3K-Akt-mTOR pathway activation might be a novel strategy to shed light on glioblastoma therapy. Video Abstract.
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