Binge drinking induces an acute burst of markers of hepatic fibrogenesis (PRO-C3).

Nikolaj TorpMads IsraelsenMette J NielsenClaus P ÅstrandPernille JuhlStine JohansenCamilla D HansenBjørn Staehr Madsen Ida Falk Villesen Diana Julie Leeming Maja Sofie ThieleTorben HansenMorten Asser KarsdalAleksander Krag

Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)

Binge drinking induced an acute burst of PRO-C3 in healthy individuals and patients with liver disease. Markers of ECM degradation were not correlated to markers of ECM formation, suggesting that even a single episode of binge drinking promotes excessive hepatic fibrogenesis.

Keyphrases

liver failure
drug induced
respiratory failure
alcohol consumption
high frequency
aortic dissection
anti inflammatory
high glucose
hepatitis b virus
intensive care unit
endothelial cells
body mass index