The optimal number of induction chemotherapy cycles in clinically lymph node-positive bladder cancer.
Markus von DeimlingLaura S MertensMarc A FurrerRoger LiGuus A H TendijckJacob TaylorFelice CrocettoMoritz MaasAndrea MariRenate PichlerMarco MoschiniKarl H TullyDavid d'AndreaEkaterina LaukhtinaFrancesco Del GiudiceGautier MarcqMaud VelevAndrea GallioliSimone AlbisinniKeiichiro MoriAbhinav KhannaMichael RinkMargit FischAndrea MinerviniPeter C BlackYair LotanPhilippe E SpiessBernhard KissShahrokh F ShariatBenjamin Praderenull nullPublished in: BJU international (2024)
Pathological response and survival outcomes did not differ between administering three or four induction chemotherapy cycles in patients with cN+ BCa. A fewer cycles (minimum three) may be oncologically sufficient in patients with cN+ BCa, while decreasing the wait for definitive local therapy in those patients who end up without a response to chemotherapy. This warrants further validation.