Infliximab regulates monocytes and regulatory T cells in Kawasaki disease.

Keiichi KoizumiMinako HoshiaiNobuyuki KatsumataTakako TodaHiroaki KiseYohei HasebeYosuke KonoYuto SunagaMasashi YoshizawaAtsushi WatanabeKeiko KagamiMasako AbeKanji Sugita

Published in: Pediatrics international : official journal of the Japan Pediatric Society (2018)

IFX could downregulate activated monocytes and upregulate Treg cells towards the normal range. IFX treatment thus contributes to the process of attenuating inflammation in KD.

Keyphrases

regulatory t cells
dendritic cells
induced apoptosis
oxidative stress
peripheral blood
cell cycle arrest
immune response
cell proliferation
cell death