A Systematic Review of Population Pharmacokinetic Models of Methotrexate.

Yiming ZhangLiyu SunXinwei ChenLibo ZhaoXiaoling WangZhigang ZhaoShenghui Mei

Published in: European journal of drug metabolism and pharmacokinetics (2022)

Various covariates could affect MTX pharmacokinetics, and their relationships have been summarized and discussed. This review will be helpful for researchers to develop their own population pharmacokinetic models and select appropriate models for individualized therapy of MTX.

Keyphrases

stem cells
mesenchymal stem cells
bone marrow