Risk factors and prognosis of bone metastases in newly diagnosed gastric cancer.
Chengtong LiangHui ChenZhanjun YangChongxu HanChuanli RenPublished in: Future oncology (London, England) (2020)
Aim: To predict the occurrence of bone metastases and prognosis among patients with gastric cancer on a population level. Materials & methods: Data were obtained from the SEER database (2010-2016). Multivariable logistic regression and multivariable Cox regression were used to determine factors that predict the occurrence of bone metastasis and prognosis. Results: Cardia cancer, younger age, white race, poor differentiation grade, higher N stage, diffuse-type were positively associated with the presence of bone metastasis. For gastric cancer patients with bone metastasis, the median survival time was longer (9.0 months) among patients with surgery of primary site compared with those without surgery (3.0 months). Conclusion: According to the results of risk assessment, clinical efforts should be targeted to focus on screening high-risk patients.
Keyphrases
- newly diagnosed
- risk assessment
- bone mineral density
- minimally invasive
- risk factors
- end stage renal disease
- coronary artery bypass
- soft tissue
- bone loss
- ejection fraction
- bone regeneration
- human health
- chronic kidney disease
- heavy metals
- postmenopausal women
- surgical site infection
- peritoneal dialysis
- cancer therapy
- low grade
- prognostic factors
- patient reported outcomes
- deep learning
- adverse drug