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The biomechanical evaluation of magnetic forces to drive osteogenesis in newborn's with cleft lip and palate.

Prasad NalabothuCarlalberta VernaMarkus SteineckAndreas Albert MuellerMichel Dalstra
Published in: Journal of materials science. Materials in medicine (2020)
This study examined the potential for dental magnets to act as a driving force for osteogenesis in the palate of newborns with a unilateral cleft lip and palate. In the first part of the study dental magnets were arranged in a set up mimicking a distraction device and the curves of the magnetic attraction force versus gap distance curves generated, with and without the presence of palatal rugae tissue in between both sides of the distraction device. The attraction forces ranged from 1 to 12 N depending on the gap distance and the presence of soft tissue in the gap. In the second part of the study these forces were used as input for a 3D finite element model of the palate of a newborn affected by unilateral cleft lip and palate. In the analysis of load transfer, it was found that the strains generated by a magnetically induced distraction exceed 1,500 µstrain suggesting that bone locally is submitted to mild overload leading to bone apposition.
Keyphrases
  • soft tissue
  • preterm infants
  • oxidative stress
  • drug induced
  • low birth weight
  • stress induced
  • diabetic rats
  • human health
  • solid phase extraction
  • finite element analysis