mTOR-dependent dysregulation of autophagy contributes to the retinal ganglion cell loss in streptozotocin-induced diabetic retinopathy.
Sanjar Batirovich MadrakhimovJin Young YangJin Ha KimJung Woo HanTae Kwann ParkPublished in: Cell communication and signaling : CCS (2021)
Collectively, our study describes the mechanisms of neurodegeneration through the hyperglycemia/ mTOR/ autophagy/ apoptosis pathway. Video Abstract.