Unraveling the role of miRNAs as biomarkers in Chagas cardiomyopathy: Insights into molecular pathophysiology.
Heriks Gomes RibeiroOny Araújo GaldinoKarla Simone Costa de SouzaAntonia Pereira Rosa NetaHui Tzu Lin-WangEdécio Cunha-NetoAdriana Augusto de RezendeVivian Nogueira SilbigerPublished in: PLoS neglected tropical diseases (2024)
In this review, we point out miR-21, miR-146b, miR-146a, miR-155, and miR-145-5p role in the complex mechanisms of ChCM. These miRNAs have been shown as potential biomarkers for precise diagnosis, reliable prognostic evaluation, and effective treatment strategies in the ChCM.