The Ablation of Sensory Neurons Expressing the Nav1.8 Sodium Channel Improves Glucose Homeostasis and Amplifies the GLP-1 Signaling in Obese Female Mice.

Marina Romaní-Pérez Clara Bullich-Vilarrubias Inmaculada López-Almela Yolanda Sanz

Published in: Molecular nutrition & food research (2023)

This data demonstrates sex-dependent differences in the Nav1.8-mediated regulation of energy metabolism, and provides new insights that may help in the design of sex-specific neuromodulation therapies for metabolic disorders induced by diets rich in fats and simple sugars.

Keyphrases

weight loss
electronic health record
adipose tissue
metabolic syndrome
high fat diet induced
spinal cord
bariatric surgery
wild type
type diabetes
blood glucose
big data
obese patients
radiofrequency ablation
machine learning
glycemic control
skeletal muscle
artificial intelligence