A potential contribution of decreased serum galectin-10 levels to systemic inflammation and pulmonary vascular involvement in systemic sclerosis.

Kentaro AwajiTakuya MiyagawaYuki FukuiSatoshi ToyamaJun OmatsuYuta NorimatsuTetsuya IkawaYusuke WatanabeAyumi YoshizakiShinichi SatoYoshihide Asano

Published in: Experimental dermatology (2021)

Decreased serum Gal-10 levels may reflect the impairment of eosinophil-mediated regulatory system for T-cell immune response in SSc, possibly contributing to pulmonary vascular involvement leading to pulmonary arterial hypertension.

Keyphrases

pulmonary arterial hypertension
systemic sclerosis
pulmonary hypertension
interstitial lung disease
pulmonary artery
immune response
transcription factor
rheumatoid arthritis
dendritic cells
inflammatory response
human health