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Genomic Resources for Asian (Elephas maximus) and African Savannah Elephant (Loxodonta africana) Conservation and Health Research.

Natalia A PradoEllie E ArmstrongJanine L BrownShifra Z GoldenbergPeter LeimgruberVirginia R PearsonJesús E MaldonadoMichael G Campana
Published in: The Journal of heredity (2023)
We provide novel genomic resources to help understand the genomic traits involved in elephant health and to aid conservation efforts. We sequence 11 elephant genomes (5 African savannah, 6 Asian) from North American zoos, including 9 de novo assemblies. We estimate elephant germline mutation rates and reconstruct demographic histories. Finally, we provide an in-solution capture assay to genotype Asian elephants. This assay is suitable for analyzing degraded museum and non-invasive samples, such as feces and hair. The elephant genomic resources we present here should allow for more detailed and uniform studies in the future to aid elephant conservation efforts and disease research.
Keyphrases
  • copy number
  • high throughput
  • healthcare
  • public health
  • gene expression
  • dna repair
  • risk assessment
  • dna methylation
  • climate change