APOE2 protects against Aβ pathology by improving neuronal mitochondrial function through ERRα signaling.

Zhiyuan NingYing LiuMengyao WanYou ZuoSiqi ChenZhongshan ShiYongteng XuHonghong LiHo KoJing ZhangSonghua XiaoDaji GuoYamei Tang

Published in: Cellular & molecular biology letters (2024)

APOE2 appears to enhance neural mitochondrial function via the activation of ERRα signaling, which may be the protective effect of APOE2 to treat AD.

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