Protein and DNA methylation-based scores as surrogate markers for interferon system activation in patients with primary Sjögren's syndrome.

Albin BjörkElina Richardsdotter AnderssonJuliana Imgenberg-KreuzGudny Ella ThorlaciusJohannes MoforsAnn-Christine SyvänenMarika KvarnströmGunnel Nordmark Marie Wahren-Herlenius

Published in: RMD open (2021)

We describe novel methods of assessing IFN system activity in plasma, serum or DNA samples, which may prove particularly valuable in studies where RNA samples are not available.

Keyphrases

dna methylation
dendritic cells
gene expression
circulating tumor
immune response
nucleic acid
single molecule
cell free
case report
protein protein
binding protein
case control
rheumatoid arthritis