Frequency of Biologically Defined Alzheimer Disease in Relation to Age, Sex, APOE ε4, and Cognitive Impairment.

Joseph TherriaultTharick A PascoalAndrea L BenedetCecile TissotMelissa SavardMira ChamounFiroza LussierMin Su KangGleb BerzginTina WangJaime Fernandes-AriasGassan MassarwehJean-Paul SoucyPaolo VitaliParamita Saha-ChaudhuriSerge GauthierPedro Rosa-Neto

Published in: Neurology (2020)

This study provides Class I evidence that biologically defined AD (abnormal amyloid PET and tau PET) was observed in 85.2% of people with clinically defined AD and 7.88% of CU elderly.

Keyphrases

cognitive impairment
computed tomography
pet ct
positron emission tomography
pet imaging
cognitive decline
mild cognitive impairment
high fat diet
type diabetes
cerebrospinal fluid
skeletal muscle
adipose tissue
community dwelling
aqueous solution