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Severe diaphragmatic dysfunction with preserved activity of accessory respiratory muscles in a critically ill child: a case report of failure of neurally adjusted ventilatory assist (NAVA) and successful support with pressure support ventilation (PSV).

Thomas LangerSerena BaioGiovanna ChidiniTiziana MarchesiGiacomo GrasselliAntonio PesentiEdoardo Calderini
Published in: BMC pediatrics (2019)
We document the failure of mechanical assistance performed with NAVA due to bilateral diaphragmatic dysfunction in a critically ill child. The preserved activity of some accessory respiratory muscles allowed to support the patient effectively with pressure support ventilation, i.e. by applying a pneumatic trigger. The present case underlines (i) the importance of the integrity of the respiratory centers, phrenic nerves and diaphragm in order to perform NAVA and (ii) the possible diagnostic role of EAdi monitoring in complex cases of weaning failure.
Keyphrases
  • mechanical ventilation
  • mental health
  • oxidative stress
  • intensive care unit
  • respiratory failure
  • respiratory tract
  • early onset
  • extracorporeal membrane oxygenation
  • drug induced