Murine Leukemia-Derived Extracellular Vesicles Elicit Antitumor Immune Response.

Alejandro PandoLoren FastPatrycja M DubieleckaAnna ChorzalskaSicheng WenJohn Reagan

Published in: Journal of blood medicine (2021)

These findings indicate that C1498-derived EVs have immunomodulatory effects on cell-mediated immune responses that could potentially be utilized to facilitate anti-leukemia immune responses.

Keyphrases

immune response
acute myeloid leukemia
bone marrow
dendritic cells
toll like receptor
cell therapy
stem cells