Egg-sensitised infants have elevated CD4 + effector memory T regulatory cells from birth.

Cristina Gamez Jonatan LefflerSharon ClarkKarli CorscaddenSusan L PrescottDebra J PalmerDeborah Strickland

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2024)

Immunological profiles associated with egg sensitisation are detectable in infant circulation at 4-6 months of age and at birth. Understanding the immune mechanisms underlying early-life sensitisation could provide important insights for future food allergy prevention strategies.

Keyphrases

early life
gestational age
regulatory t cells
transcription factor
working memory
current status
nk cells
pregnant women
type iii
immune response