Feasibility and safety of calcium alginate hydrogel sealant for the treatment of cryptoglandular fistula-in-ano: phase I/IIa clinical trial.

Fernando de la PortillaSandra Dios BarbeitoMaría Victoria Maestre-SánchezJorge Manuel Vázquez-MonchulAna María García-CabreraIrene RamalloMaría Luisa Reyes-Díaz

Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)

The treatment was feasible, safe and with discrete satisfactory healing results. It also demonstrated an acceptable safety profile, without worsening of faecal incontinence, quality of life and pain following treatment.

Keyphrases

clinical trial
drug delivery
chronic pain
combination therapy
study protocol
replacement therapy
wound healing
tissue engineering