Molecular profiling of appendiceal serrated lesions, polyps and mucinous neoplasms: a single-centre experience.

Giada MunariGianluca BusinelloPaola MattioloGianmaria PennelliMarta SbaragliaChiara BorgaSalvatore PucciarelliGaya SpolveratoClaudia MescoliFrancesca GaluppiniAntonio SommarivaElena BellanSara LonardiFotios LoupakisClaudio LuchiniAngelo Paolo Dei TosAngelo Paolo Dei Tos

Published in: Journal of cancer research and clinical oncology (2021)

The histological phenotypic similarities between appendicular mucinous lesions and serrated colon lesions do not reflect a similar genetic landscape. Mismatch repair deficiency is a rare event during appendiceal mucinous carcinogenesis.

Keyphrases

low grade
high grade
single cell
gene expression
copy number