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Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation.

Ling WangCourtney E Sparacino-WatkinsJun WangNadeem WajihPaul VaranoQinzi XuEric CeccoJesús TejeroManoocher SoleimaniDaniel B Kim-ShapiroMark T Gladwin
Published in: British journal of pharmacology (2019)
These studies suggest that human, bovine and mouse CAII are not responsible for nitrite-dependent NO formation in red blood cells, aorta, or the systemic circulation.
Keyphrases
  • nitric oxide
  • red blood cell
  • nitric oxide synthase
  • endothelial cells
  • hydrogen peroxide
  • induced pluripotent stem cells
  • drug induced