Carbonic anhydrase II does not regulate nitrite-dependent nitric oxide formation and vasodilation.
Ling WangCourtney E Sparacino-WatkinsJun WangNadeem WajihPaul VaranoQinzi XuEric CeccoJesús TejeroManoocher SoleimaniDaniel B Kim-ShapiroMark T GladwinPublished in: British journal of pharmacology (2019)
These studies suggest that human, bovine and mouse CAII are not responsible for nitrite-dependent NO formation in red blood cells, aorta, or the systemic circulation.