Prognostic models for mortality risk in patients requiring ECMO.

Lara C A PladetJaimie M M BartenLisette M VernooijCarlos V Elzo KraemerJeroen J H BungeErik ScholtenLeon J MontenijMarijn KuijpersDirk W DonkerOlaf L CremerChristiaan L Meuwese

Published in: Intensive care medicine (2023)

A large number of mortality prediction models have been developed for ECMO patients, yet only a minority has been externally validated. Furthermore, we observed only moderate predictive performance, large heterogeneity between-study populations and model performance, and poor methodological quality overall. Most importantly, current models are unsuitable to provide decision support for selecting individuals in whom initiation of ECMO would be most beneficial, as all models were developed in ECMO patients only and the decision to start ECMO had, therefore, already been made.

Keyphrases

extracorporeal membrane oxygenation
end stage renal disease
ejection fraction
acute respiratory distress syndrome
newly diagnosed
respiratory failure
cardiovascular disease
intensive care unit
type diabetes
patient reported outcomes
risk factors
quality improvement
mechanical ventilation