Cluster-randomized controlled trial of intermittent preventive treatment in infancy using sulfadoxine-pyrimethamine (SP-IPTi): a pilot study in Nigeria.
Olumide Thomas AdelekeAbayomi OyenugaTina M SlusherDaniel A GbaderoPublished in: Journal of tropical pediatrics (2023)
Our study demonstrated that SP-IPTi had no benefit but was well tolerated. WHO and some researchers have also reported declining efficacy of SP, due to increasing drug resistance.