Rehmanniae Radix Preparata suppresses bone loss and increases bone strength through interfering with canonical Wnt/β-catenin signaling pathway in OVX rats.

C LiuL WangR ZhuH LiuR MaB ChenL LiY GuoQ JiaS ShiD ZhaoF MoB ZhaoJ NiuM FuA N OrekhovD BrömmeS GaoDongwei Zhang

Published in: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA (2018)

RRP attenuates bone loss and improves bone quality in OVX rats partly through its regulation of the canonical Wnt/β-catenin signaling pathway, suggesting that RRP has the potential to provide a new source of anti-osteoporotic drugs.

Keyphrases

bone loss
cell proliferation
stem cells
bone mineral density
signaling pathway
quality improvement
human health
climate change
soft tissue