Using the Bayesian variational spike and slab model in a genome-wide association study for finding associated loci with bipolar disorder.
Maryam Kazemi NaeiniMahdi AkbarzadehIraj KazemiDoug SpeedSayed Mohsen HosseiniPublished in: Annals of human genetics (2023)
By reducing the statistical restrictions of GWAS analysis, the application of the Bayesian variational spike and slab models can offer insight into the genetic link with BD even with a small sample size. To uncover related variations with other traits, this model needs to be further examined.