Impact of Down Syndrome on Survival Among Patients With Congenital Heart Disease.
Stella EngsnerKok Wai GiangMikael DellborgMaria FedchenkoPeter ErikssonZacharias MandalenakisPublished in: Journal of the American Heart Association (2024)
In this retrospective cohort study, the mortality risk among patients with CHD-DS was 25 times higher compared with matched controls and 2 times higher compared with patients with CHD without DS. Survival was higher in patients with CHD-DS born after versus before 1990, coinciding with the modern era of congenital heart care.