T-cell immunity against SARS-CoV-2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with Delta or Omicron variants.
Marta Fernández-GonzálezVanesa AgullóJose Alberto Garcia-GómezSergio PadillaJavier García-AbellánAlba de la RicaPaula MascarellMar MasiáFelix GutiérrezPublished in: The Journal of infectious diseases (2023)
Pre-existing immunity against SARS-CoV-2 is strongly associated with patient outcomes in vaccinated individuals requiring hospital admission for COVID-19. Persons showing both T-cell and antibody responses have the lowest risk of severe outcomes.