T-cell immunity against SARS-CoV-2 measured by an interferon-γ release assay is strongly associated with patient outcomes in vaccinated persons hospitalized with Delta or Omicron variants.

Marta Fernández-González Vanesa Agulló Jose Alberto Garcia-Gómez Sergio Padilla Javier García-Abellán Alba de la Rica Paula Mascarell Mar Masiá Felix Gutiérrez

Published in: The Journal of infectious diseases (2023)

Pre-existing immunity against SARS-CoV-2 is strongly associated with patient outcomes in vaccinated individuals requiring hospital admission for COVID-19. Persons showing both T-cell and antibody responses have the lowest risk of severe outcomes.

Keyphrases

sars cov
respiratory syndrome coronavirus
emergency department
healthcare
high throughput
copy number
dendritic cells
adverse drug
immune response
drug induced
skeletal muscle