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Clinical and radiological characteristics of acute pulmonary embolus in relation to 28-day and 6-month mortality.

Lindsey NortonGordon CooperOwen SheerinsKillian Mac A' BháirdGiles RoditiMichael AdamsonDavid YoungRoss DolanColin ChurchAdrian J B BradyCampbell TaitGraham McKenzieAlasdair McFadyenMatthew ZelicDonogh Maguire
Published in: PloS one (2021)
PESI score >100, poGPS≥1, NLR ≥3 and CAC score ≥6 were associated with 28-day and 6-month mortality. PESI score ≥100, poGPS≥1 and NLR ≥3 remained independently associated with 28-day mortality. PESI score ≥100 and CAC score ≥6 remained independently associated with 6-month mortality. When patients with underlying cancer were excluded from the analysis, GPS≥1 remained independently associated with 6-month mortality. The role of the systemic inflammatory response (SIR) in determining treatment and prognosis requires further study. Routine reporting of CAC scores in CTPA scans for acute PE may have a role in aiding clinical decision-making regarding treatment and prognosis.
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