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Induction of ferroptosis-like cell death of eosinophils exerts synergistic effects with glucocorticoids in allergic airway inflammation.

Yanping WuHaixia ChenNanxia XuanLingren ZhouYinfang WuChen ZhuMiao LiQingyu WengJiaxin ShenHao ZhangBin ZhangFen LanLixia XiaXuefang XiongZhou-Yang LiYun ZhaoMindan WuSongmin YingWen LiHuahao ShenZhihua Chen
Published in: Thorax (2020)
FINs induced ferroptosis-like cell death of eosinophils, suggesting their use as a promising therapeutic strategy for eosinophilic airway inflammation, especially due to the advantage of their synergy with GCs in the treatment of allergic disorders.
Keyphrases
  • cell death
  • cell cycle arrest
  • allergic rhinitis
  • diabetic rats
  • oxidative stress
  • cell proliferation
  • chronic rhinosinusitis