Loss of Airway Phylogenetic Diversity Is Associated with Clinical and Pathobiological Markers of Disease Development in COPD.
Kristopher OpronLesa A BegleyJohn R Erb-DownwardGen LiNeil E AlexisIgor BarjaktarevicR Graham BarrEugene R BleeckerRichard BoucherRussell P BowlerStephanie A ChristensonAlejandro P ComellasGerard CrinerChristopher B CooperDavid CouperCraig J GalbanMeiLan K HanAnnette T HastieCharles HattEirc A HoffmanRobert J KanerMehmet KesimerJerry A KrishnanDavid C LaFonFernando J MartinezVictor E OrtegaStephen P PetersRobert Paine IiiNirupama PutchaPrescott G WoodruffGary B HuffnagleAriangela J KozikJeffrey L CurtisYvonne Jean Huangnull nullPublished in: American journal of respiratory and critical care medicine (2024)
In SPIROMICS baseline airway microbiota features demonstrate divergent associations with better or worse COPD-related outcomes.