Early biomarkers of extracapsular extension of prostate cancer using MRI-derived semantic features.
Adalgisa GuerraFilipe Caseiro AlvesKris MaesSteven JoniauJoão CassisRui MaioMarília CravoHelena MouriñoPublished in: Cancer imaging : the official publication of the International Cancer Imaging Society (2022)
Our predictive model, based on consistent MRI features (i.e., measurable ECE and TCCL) and a prostate biopsy GS, has satisfactory performance and sufficiently high sensitivity for predicting pECE+. Hence, the model could be a valuable tool for surgeons planning preoperative nerve sparing, as it would reduce positive surgical margins.