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Design differences explain variation in results between randomized trials and their non-randomized emulations.

Rachel HeyardLeonhard HeldSebastian G SchneeweissShirley V Wang
Published in: medRxiv : the preprint server for health sciences (2023)
A large share of the observed variation in results between RCT-RWE study pairs could be explained by design emulation differences.
Keyphrases
  • double blind
  • open label
  • phase iii