Efficacy and safety of botulinum toxin for treating sialorrhea: A systematic review and meta-analysis.

Ya-Chien YuChen-Chih ChungYu-Kang TuChien-Tai HongKee-Hsin ChenKa-Wai TamYi-Chun Kuan

Published in: European journal of neurology (2021)

There is moderate certainty of evidence (COE) that either BoNT-A or BoNT-B could relieve sialorrhea after 4 and 12 weeks of follow-up without significantly more severe AEs in adults. However, the COE is very low to low in children.

Keyphrases

botulinum toxin
young adults
high intensity
early onset
drug induced