Lack of skin manifestations in COVID-19 hospitalized patients during the second epidemic wave in Spain: a possible association with a novel SARS-CoV-2 variant - a cross-sectional study.

The Coronavirus Disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Skin lesions have been described in confirmed COVID-19 patients as potential manifestations of the disease1 . Different prevalence rates have been reported in hospitalized patients from January to May 2020, ranging from 0.2 to 20.5%.2-5 Prevalence rates in studies where dermatologists did not perform the initial physical examination may be underestimated2,5,6 . A second wave of the COVID-19 epidemic has emerged in European countries starting in late August. Spain has been one of the most affected regions. However, cutaneous findings have been scarcely reported during this time period.