Liraglutide increases islet Ca 2+ oscillation frequency and insulin secretion by activating hyperpolarization-activated cyclic nucleotide-gated channels.
Karolina E ZaborskaKelli L JordanAriel S ThorsonPrasanna K DadiCharles M SchaubArya Y NakheMatthew Thomas DickersonJoshua C LynchAdam J WeissJordyn R DobsonDavid Aaron JacobsonPublished in: Diabetes, obesity & metabolism (2022)
oscillation frequency and somatostatin secretion kinetics in a β-cell-dependent manner.