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Toxicological Impact of Bisphenol A on Females' Reproductive System: Review Based on Experimental and Epidemiological Studies.

Shahla ChaichianFatemeh KhodabandehlooLadan HaghighiAzam GovahiMehdi MehdizadehMarziyeh AjdaryRajender S Varma
Published in: Reproductive sciences (Thousand Oaks, Calif.) (2024)
The study encompassing research papers documented in the last two decades pertaining to the possible influence of bisphenol A (BPA) on the fertility of females are appraised with emphasis on the influence of BPA in reproductive organs (uterus and ovaries) and pregnancy outcomes including discussion on the reproductive process (implantation, estrous cycle, hormone secretion); outcomes reveal a connection amongst BPA and female infertility. Ovary, uterus, and its shape as well as function can alter a person's ability to become pregnant by influencing the hypothalamus-pituitary axis in the ovarian model. Additionally, implantation and the estrous cycle may be affected by BPA. However, more research is warranted to comprehend the underlying action mechanisms and to promptly identify any imminent reproductive harm.
Keyphrases
  • pregnancy outcomes
  • pregnant women
  • type diabetes
  • genome wide
  • gene expression
  • metabolic syndrome
  • young adults
  • polycystic ovary syndrome
  • oxide nanoparticles