Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells.
Narges BayatNathan McOristNicholas AriottiMay LaiKeith Cs SiaYuhuan LiJames L GraceJohn F QuinnMichael R WhittakerMaria KavallarisThomas P DavisRichard B LockPublished in: International journal of nanomedicine (2019)
Thiol-reactive star polymers having an mPEG brush corona that includes a proportion of diethylene glycol brush moieties represent a potential strategy for improved leukemia cell delivery.
Keyphrases
- acute lymphoblastic leukemia
- induced apoptosis
- cell cycle arrest
- single cell
- acute myeloid leukemia
- bone marrow
- cell therapy
- allogeneic hematopoietic stem cell transplantation
- quantum dots
- endoplasmic reticulum stress
- oxidative stress
- stem cells
- mesenchymal stem cells
- risk assessment
- high resolution
- cell proliferation
- mass spectrometry