Metabolic profiling of smoking, associations with type 2 diabetes and interaction with genetic susceptibility.

Yuxia WeiSara HäggJonathan K L MakTiinamaija TuomiYiqiang ZhanSofia Carlsson

Published in: European journal of epidemiology (2024)

The increased risk of T2D in smokers may be mediated through effects on the metabolome, and the influence of such metabolic alterations on diabetes risk may be amplified in individuals with genetic susceptibility to T2D or insulin resistance.

Keyphrases

insulin resistance
type diabetes
smoking cessation
genome wide
cardiovascular disease
copy number
glycemic control
metabolic syndrome
high fat diet
single cell
skeletal muscle
gene expression
dna methylation
weight loss